Clinical Efficacy of Dapoxetine 60mg in Studies

Our prescribers can guide you to the most suitable treatment during a quick online consultation.

What is the satisfaction rate with dapoxetine?

Discuss your Priligy treatment with tadalafil with dapoxetine online your prescriber after the first 4 weeks or after 6 doses to see whether you should continue treatment. If treatment is continued, you should see your prescriber again to discuss this at least every six months. Premature ejaculation (PE) is one of the most common male sexual health concerns in the UK, affecting an estimated 1 in 3 men at some point in their lives. It occurs when a man ejaculates sooner than he or his partner would like during sexual activity - typically within one to two minutes of penetration. Occasional episodes are completely normal and not a cause for concern.

Therapeutic Categories

However, when PE happens consistently and causes distress or affects relationships, effective prescription and over-the-counter treatments are available through AYP Healthcare's online clinic, without the need for a GP visit. There are two main types of treatment for premature ejaculation available in the UK. Oral prescription tablets, specifically Priligy (dapoxetine), are taken on-demand before sexual activity and work by delaying the ejaculation reflex. Topical treatments - such as STUD 100 desensitising spray and EMLA cream, are applied directly to the penis to temporarily reduce sensitivity and help prolong intercourse. Both approaches are clinically proven, and the right option depends on personal preference, medical history, and whether you prefer a prescription or non-prescription solution. Priligy contains dapoxetine, a fast-acting selective serotonin reuptake inhibitor (SSRI) specifically developed for the treatment of premature ejaculation. Unlike other SSRIs taken daily, Priligy is designed to be taken on-demand , typically 1 to 3 hours before sexual activity. It works by increasing serotonin activity in the nervous system, which delays the ejaculatory reflex and gives men significantly greater control.

Product	Dosage	Quantity + Bonus	Price
Priligy Generic Dapoxetine	60mg	10 Pills	47.63€ 45.36€	Buy
Viagra Generic	25mg	30 + 4 Pills	47.97€ 45.69€	Buy
Kamagra Oral Jelly	100 mg	110 + 9 Sachets	334.87€ 318.92€	Buy
Priligy Generic Dapoxetine	60mg	180 + 10 Pills	494.76€ 471.20€	Buy
Priligy Generic Dapoxetine	60mg	60 + 8 Pills	183.06€ 174.34€	Buy
Tadalista Super Active	20mg	30 + 6 Pills	128.09€ 121.99€	Buy
Kamagra Polo	100mg	180 + 8 Pills	446.52€ 425.26€	Buy
Kamagra Polo	100 mg	60 + 4 Pills	189.39€ 180.37€	Buy
Priligy Generic Dapoxetine	60mg	20 + 4 Pills	77.31€ 73.63€	Buy
Priligy Generic Dapoxetine	60mg	30 + 6 Pills	106.65€ 101.57€	Buy
Priligy Generic Dapoxetine	60mg	90 + 10 Pills	265.64€ 252.99€	Buy
Levitra Generic	40mg	180 + 10 Pills	405.06€ 385.77€	Buy
Priligy Generic Dapoxetine	60mg	120 + 10 Pills	341.26€ 325.01€	Buy

Clinical studies have shown it can increase the time to ejaculation by up to three times. Priligy is dapoxetine 30mg tablet available in 30mg and 60mg strengths and is a prescription-only medicine, available through AYP Healthcare following a brief online consultation. Yes , topical desensitising products containing lidocaine are a well-established, non-prescription option for premature ejaculation. STUD 100 spray and EMLA cream work by mildly numbing the surface of the penis, reducing sensitivity and helping to delay ejaculation. They are applied a short time before intercourse and are discreetly available without a prescription. These products are particularly popular among men who prefer not to take oral medication or who are looking for an on-the-spot solution with minimal side effects. Using a condom after applying topical treatments is recommended to prevent the numbing effect transferring to a partner. Yes , provided you use a GPhC-regulated online pharmacy such as AYP Healthcare.

• Overdose may present with serotonin syndrome: agitation, hyperthermia, tremor, and clonus.
• Management is supportive; no specific antidote exists; seek immediate medical attention.
• Dialysis is unlikely to remove dapoxetine effectively due to high protein binding.

Our online clinic is fully regulated, and all prescription treatments such as Priligy (dapoxetine) are only dispensed after a qualified prescriber has reviewed your consultation and confirmed suitability.

Contraindication	Explanation	Precautionary Measures
Severe hepatic impairment	Impaired drug metabolism	Dose adjustment or avoid use
Concurrent use with MAO inhibitors	Risk of serotonin syndrome	Discontinue MAO inhibitors before use
Heart problems	Potential cardiovascular side effects	Consult physician before use
Allergies to dapoxetine or excipients	Possible allergic reactions	Discontinue and seek medical advice

Non-prescription topical treatments like STUD 100 spray can be purchased directly.

PCI DSS Compliant

thyroid problems – an overactive thyroid or an underactive thyroid anxiety about sexual performance (particularly at the start of a new relationship or when a man has had previous problems with sexual performance) Priligy contains an active substance called dapoxetine. It belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs) and may also be known as a ‘urological’ medicine. It acts much faster than the other SSRIs used for premature ejaculation and can be used "on-demand". You'll usually be advised to take it between 1 and 3 hours before sex, but not more than once a day. Priligy increases the time it takes to ejaculate and can improve the control over the ejaculation.

2.1 Chemical Structure and Classification

This may reduce the frustration or worry about fast ejaculation. Priligy is used to treat premature ejaculation in adult men aged 18 to 64 years. Premature ejaculation is when a man ejaculates with little sexual stimulation and before the man wants. This can cause problems for the man and may cause problems in sexual relationships. Dapoxetine is not suitable for all men diagnosed with premature ejaculation. All orders are dispensed by our pharmacist and delivered in plain, discreet packaging - so there is no need to visit a GP surgery or pharmacy in person. Yes , psychological factors are among the most common causes of premature ejaculation. Performance anxiety, stress, relationship difficulties, and low confidence can all contribute to or worsen PE. This is especially true for men experiencing it at the start of a new relationship or following a period of sexual inactivity. In many cases, a combination of effective treatment alongside techniques such as the stop-start method, pelvic floor exercises, or psychosexual counselling can produce the best long-term results.

Patient Profile	Recommended Dose	Frequency	Special Considerations
Adult Men with PE	60 mg taken 1-3 hours before sexual activity	As needed, max once daily	Do not exceed once daily
Men with Liver Impairment	Dose adjustment or avoid use	Under medical supervision	Liver function tests recommended
Elderly Men	Same as standard dose	Monitor for side effects	Increased sensitivity possible

If you feel your PE is primarily psychological in nature, it is worth mentioning this during your online consultation so your prescriber can provide the most appropriate advice.

Interacting Drug Class	Effect on Dapoxetine	Potential Risks
CYP3A4 inhibitors	Increased plasma levels	Higher risk of side effects
Serotonergic drugs (SSRIs, MAOIs)	Risk of serotonin syndrome	Serious neurological symptoms
Alcohol	Enhanced sedative effects	Dizziness, impaired coordination
Other PDE5 inhibitors	Possible additive effects	Hypotension

I'm pleased to say I am totally satisfied with the professional way I was treated.

Why is Priligy priced so high?

For example, it is not recommended for some men with heart, kidney and liver problems. It can also interact with other medicines, such as other antidepressants. Always take this medicine exactly as your doctor, pharmacist, or prescriber has told you. If you are unsure, check with them. Your prescriber may increase the dose to 60 mg.

Search strategy

Only take the medicine 1 to 3 hours before sexual activity is anticipated. Do not take this medicine more than once every 24 hours or daily. Swallow the tablets whole to avoid a bitter taste, with at least one full glass of water. This medicine can be taken with or without food. This medicine should not be used by men under 18 or over 65 years of age. UK Registered Pharmacy The MHRA regulates medicines and medical devices in the UK.

• In Japan, dapoxetine 60 mg was approved in 2021, marketed under brand names like Priligy.
• Other brands include Joy-Pox, Dapex, and Duralast; generic versions available in some regions.
• Ensure genuine product from licensed pharmacies to avoid counterfeit tablets.

The MHRA regulates medicines and medical devices in the UK. GPhC Regulated Pharmacy The GPhC regulates pharmacists, pharmacy technicians and pharmacies in Great Britain. The GPhC regulates pharmacists, pharmacy technicians and pharmacies in Great Britain.

Safety Assessments

"New agents in the treatment of premature ejaculation". "Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials". "Dapoxetine has long-term efficacy in the treatment of premature ejaculation". "AUA guideline on the pharmacologic management of premature ejaculation". "Dapoxetine: An Innovative Approach in the Therapeutic Management In Animal Model of Depression".

Phosphodiesterase 5 inhibitors

"Antistress and antidepressant properties of dapoxetine and vortioxetine". "Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase 3 trial in 22 countries". "Discontinuation of Dapoxetine Treatment in Patients With Premature Ejaculation: A 2-Year Prospective Observational Study". "Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction". PCI DSS Compliant PCI DSS is an information security standard for organisations that handle credit card payments. PCI DSS is an information security standard for organisations that handle credit card payments.

Buy Dapoxetine 60 mg Tablets Online: Discounted Prices & FREE Shipping

"Dapoxetine-A Novel Drug for Premature Ejaculation". "Dapoxetine for the treatment of premature ejaculation: Lack of interaction with ethanol". "Monoaminergic transporter binding and inhibition profile of dapoxetine, a medication for the treatment of premature ejaculation". "Physiology of ejaculation: emphasis on serotonergic control". "Supraspinal site of action for the inhibition of ejaculatory reflex by dapoxetine".

Patient-reported global impression of change (PGIC)

"Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials". ^ "Dapoxetine: a guide to its use in premature ejaculation". "Pharmacokinetics of single and multiple escalating doses of dapoxetine in healthy volunteers". "Cardiovascular safety profile of dapoxetine during the premarketing evaluation". "Suicide rates in clinical trials of SSRIs, other antidepressants, and placebo: analysis of FDA reports". ICO Registered Website The UK's independent authority set up to uphold information rights in the public interest.

What does Priligy do to your body?

"Selective serotonin reuptake inhibitor discontinuation syndrome: a review". "Emerging treatments for premature ejaculation: focus on dapoxetine". "Dapoxetine: a novel treatment for premature ejaculation". "Stereoselective synthesis of tab dapoxetine 30 mg (S)-dapoxetine starting from trans-cinnamyl alcohol". "Medical Non-Endocrine-Targeted Therapies: Ejaculatory Dysfunction and Immunotherapy".

CAS registry number (Chemical Abstracts Service)

Premature ejaculation is a common ejaculation problem. This is when the male ejaculates sooner than he or his partner wishes during sexual arousal and activity. This can happen occasionally and is not a cause for concern! However, if it happens more than you'd like and is a problem, it might help to get treatment. Various psychological and physical factors can cause a man to suddenly experience premature ejaculation. The UK's independent authority set up to uphold information rights in the public interest. Priligy, the brand name for dapoxetine, is a pharmacological agent primarily indicated for the treatment of premature ejaculation (PE) in adult men. Premature ejaculation is one of the most common sexual dysfunctions affecting men worldwide, characterized by ejaculation that occurs sooner than desired, causing distress and interpersonal difficulties. Priligy represents a novel approach to managing PE as it is the first drug specifically approved for this condition in many countries. This article provides an in-depth analysis of Priligy’s pharmacology, clinical uses, mechanism of action, dosage, side effects, and particular considerations for healthcare professionals and patients.